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Classe de systèmes d'organes MedRA Termes préférés Fréquents ≥ 1/100 à < 1/10 Rares ≥ 1/1000 à < 1/100 Affections psychiatriques Symptômes émotionnels* (sautes d'humeur, troubles affectifs, colère, agressivité, impatience, insomnie, rêves anormaux, augmentation de la libido) Affections vasculaires Hypertension maligne, bouffées vasomotrices, phlébite Affections gastro-intestinales Diarrhée, distension abdominale, douleurs buccales Affections de la peau et du tissu sous-cutané Réactions cutanées* (acné, alopécie, sècheresse de la peau, lésions cutanées, dermatite de contact, modifications de la couleur des cheveux, éruption cutanée, hypersensibilité, prurit au niveau du site d'application) Affections des organes de reproduction et du sein Gynécomastie, troubles au niveau des mamelons, douleurs testiculaires, érections accrues Troubles généraux et anomalies au site d'administration Œdème qui prend le godet Investigations PSA accru, augmentation de l'hématocrite ou de l'hémoglobine. 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